Mutation without Selection

I am by no means an expert in genetics, so I’m reading through an article on PLOS Biology (Referred by ScienceDaily, credit where credit is due) which reports some interesting findings. Apparently there are geners that are evolving at a faster rate than normal with AT-to-GC biased substitutions. Apparently a number of the mutations are actually harmful. The authors are calling this Biased-Gene Conversion. The article states that they don’t expect this BGC bias only in human exons, and they expect different exons to be affected in different species.

I don’t know what all of this means as far as the big picture goes. Anyone out there with sufficient knowledge to explain it?


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